BREAST CANCER FACT SHEET


WHAT IS BREAST CANCER?

Breast cancer is a malignant tumor that has developed from cells within the breast.


HOW COMMON IS IT?

The Philippines is ranked first in breast cancer incidence in Asia and has a higher prevalence rate than those in several Western countries, including Spain, Italy, and most Eastern European countries.

Breast cancer is the leading cause of cancer and cancer deaths in Filipino women.


ARE THERE DIFFERENT TYPES OF BREAST CANCER?

The two kinds of non-invasive breast cancer are ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS). Starting in either the milk passages (ducts) or the milk-producing glands (lobules), these cancers do not penetrate beyond the walls into surrounding tissues.

The two most prevalent types of invasive breast cancer also either start in the ducts or the lobules, however these cancers have the potential to involve the fatty tissue of the breast. From this point, it may spread (metastasize) to other parts of the body.

  • Invasive ductal carcinoma is the most common type of breast cancer, accounting for about 80 percent of breast malignancies.
  • Lobular carcinoma accounts for about 10 percent of invasive breast cancers.
  • Other types of invasive breast cancer include inflammatory breast cancer and metaplastic breast cancer.

  • WHAT IS ADVANCED BREAST CANCER?

    Advanced breast cancer describes stages of cancer where the disease has spread from the primary site to other parts of the body. This is also known as metastatic breast cancer.

    The five-year relative survival rate is lower among women with a more advanced stage of cancer at diagnosis.


    WHAT IS THE PROGNOSIS FOR WOMEN WITH BREAST CANCER?

    Based on the most recent data, relative survival rates for women diagnosed with breast cancer are: 88 percent at 5 years after diagnosis, 80 percent after 10 years, 71 percent after 15 years and 63 percent after 20 years.

    From 1990 to 2002, death rates have decreased. The decline has been attributed to both improvements in breast cancer treatment and early detection.


    WHAT ARE THE RISK FACTORS ASSOCIATED WITH BREAST CANCER?

    Some known risk factors for breast cancer include: family history of the disease especially in a mother or sister, beginning menstrual periods at a young age (early menarche) and ending periods at an older age (late menopause), genetic factors and obesity.


    WHAT ARE THE CURRENT TREATMENT OPTIONS FOR WOMEN WITH BREAST CANCER?

    The current methods of treatment in use are: radiation, chemotherapy, hormonal therapy, and biological therapy, including, monoclonal antibody therapy and finally surgery (mastectomy and lumpectomy).

    There is a constant search for new and better ways to treat breast cancer. Advances over the last few decades have extended survival and improved the quality of life of breast cancer patients.

    Some of the most exciting new treatments are the targeted therapies that, unlike many of today’s standard treatments, are designed to attack the cancer cells while leaving normal cells unharmed. Such targeted therapies can help limit side effects and potentially improve survival.




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    Philippines

    GSK at a glance

    We are the only pharmaceutical company to tackle the three "priority" diseases identified by the World Health Organization: HIV/AIDS, tuberculosis and malaria
    Our business employs over 100,000 people in 117 countries
    We make almost four billion packs of medicines and healthcare products every year
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    We supply one quarter of the world's vaccines and by the end of 2007 we had 23 vaccines in clinical development
    To date, we have donated over 750 million albendazole tablets to help elimitate lymphatic filariasis (elephantiasis) in the world
    In 2006 we shipped 126 million tablets of preferentially-priced Combivir and Epivir (our HIV treatments) to developing countries
    Almost 100 countries benefitted from our humanitarian product donations


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    Updated July 2007 by GlaxoSmithKline Philippines.
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